Probiotic ‘backpacks’ can treat inflammatory bowel disease at any stage
Well-equipped, gut-friendly bacteria can help treat inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, according to a new study.
Combined with probiotics, nanoparticle backpacks could significantly improve, and simplify, IBD treatments, according to research at the University of Wisconsin–Madison in the US which was led by Quanyin Hu, a biomedical engineer and professor.
They’ve also figured out a way of attaching these nanoparticle “backpacks” to beneficial bacteria after encasing them in a protective coating.
The nanoparticle backpacks are part sulfide and part hyaluronic acid. The acid is powerfully anti-inflammatory, and the sulfide directly targets the reactive oxygen species.
Conducted in mice, the researchers estimated the effects of the treatments in two ways: by measuring changes in weight and changes in the colon length of mice with IBD that did and did not receive the treatment.